| Identification | Back Directory | [Name]
AMG 837 (sodiuM salt) | [CAS]
865231-45-4 | [Synonyms]
AMG-837 Sodium
AMG 837 (sodiuM salt) | [Molecular Formula]
C26H22F3NaO3 | [MDL Number]
MFCD28155268 | [MOL File]
865231-45-4.mol | [Molecular Weight]
462.44 |
| Hazard Information | Back Directory | [Uses]
AMG 837 (sodium salt) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Lin DC, et al. AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents. PLoS One. 2011;6(11):e27270. DOI:10.1371/journal.pone.0027270
[2] Houze JB, et al. AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70. DOI:10.1016/j.bmcl.2011.10.118 |
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