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868169-64-6

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868169-64-6 Structure

868169-64-6 Structure
IdentificationBack Directory
[Name]

IMetelstat
[CAS]

868169-64-6
[Synonyms]

GRN-163L
IMetelstat
Hazard InformationBack Directory
[Uses]

Imetelstat is an 13‐mer oligonucleotide that binds with high affinity to the template region of the RNA component of human telomerase and acts as a competitive inhibitor of human telomerase enzymatic activity[1].
[References]

[1] Ashley L Lennox, et al. Imetelstat, a novel, first-in-class telomerase inhibitor: Mechanism of action, clinical, and translational science. Review Clin Transl Sci. 2024 Nov;17(11):e70076. DOI:10.1111/cts.70076
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