| Identification | Back Directory | [Name]
pyrimorph | [CAS]
868390-90-3 | [Synonyms]
pyrimorph
Pyrimorph Solution in Methanol, 100μg/mL
2-Propen-1-one, 3-(2-chloro-4-pyridinyl)-3-[4-(1,1-dimethylethyl)phenyl]-1-(4-morpholinyl)- | [Molecular Formula]
C22H25ClN2O2 | [MDL Number]
MFCD32655087 | [MOL File]
868390-90-3.mol | [Molecular Weight]
384.9 |
| Chemical Properties | Back Directory | [Melting point ]
131-133°C | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), DMSO (Slightly) Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChI]
InChI=1S/C22H25ClN2O2/c1-22(2,3)18-6-4-16(5-7-18)19(17-8-9-24-20(23)14-17)15-21(26)25-10-12-27-13-11-25/h4-9,14-15H,10-13H2,1-3H3 | [InChIKey]
QEUOHPLVFSQWME-UHFFFAOYSA-N | [SMILES]
C(N1CCOCC1)(=O)C=C(C1C=CN=C(Cl)C=1)C1=CC=C(C(C)(C)C)C=C1 |
| Hazard Information | Back Directory | [Uses]
Pyrimorph is a novel fungicide. | [Production Methods]
Commercial production of pyrimorph follows the typical industrial strategy for assembling cinnamic acid–derived amide fungicides. Manufacturers begin with a substituted cinnamic acid precursor, which is activated, often via conversion to the corresponding acid chloride, to enable efficient coupling. This activated intermediate is then reacted with a morpholine based amine, forming the characteristic amide linkage that defines pyrimorph’s fungicidal profile. Process controls focus on maintaining stereochemical integrity of the cinnamic backbone, suppressing over acylation of the morpholine ring. | [Mechanism of action]
Multiple modes of action including the inhibition of mycelial growth, sporangium production and zoospore release | [in vivo]
Pyrimorph (0-28 mg/L; exposure; 0-192 h) has low toxicity and accumulates quickly in zebrafish[2]. | Animal Model: | Zebrafish (Brachydanio rerio), with an average body weight and length of about 0.30±0.10 g and 3.00±0.50 cm, respectively[2] | | Dosage: | 0-28 mg/L | | Administration: | Exposure, 0-192 h | | Result: | Had low toxicity to zebrafish, with LC50 values ranging from 24.33 mg/L (24 h) to 19.79 mg/L (96 h). Accumulated in fish shortly. |
| [Pesticide Type]
Fungicide |
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