| Identification | Back Directory | [Name]
hexadecanesulfonyl fluoride | [CAS]
86855-26-7 | [Synonyms]
hexadecanesulfonyl fluoride
QIVFMUVBIHIZAM-UHFFFAOYSA-N
1-Hexadecanesulfonyl fluoride
Hexadecane-1-sulfonyl fluoride | [Molecular Formula]
C16H33FO2S | [MOL File]
86855-26-7.mol | [Molecular Weight]
308.5 |
| Hazard Information | Back Directory | [Uses]
AM 374 is a potent in vitro and in vivo inhibitor of fatty acid amide hydrolase (FAAH). | [Definition]
ChEBI: Hexadecane-1-sulfonyl fluoride is an acyl fluoride. It is functionally related to a hexadecane-1-sulfonic acid. | [in vivo]
AM 374 (20 μg; i.c.v., once) shows no effect on FR5 lever pressing but reduces lever pressing combined with IP injections of anandamide[2]. | Animal Model: | Adult male Sprague-Dawley rats with lever press training[2] | | Dosage: | 20 μg | | Administration: | Intraventricular (ICV) injection; 20 μg, once | | Result: | Significantly reduced lever pressing when combined treatment with anandamide.
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