| Identification | Back Directory | [Name]
13-(dimethylamino)-5-(4-methylphenyl)-8-thia-3,5,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one | [CAS]
869802-73-3 | [Synonyms]
Pyrido[4',3':4,5]thieno[3,2-d]pyrimidin-4(3H)-one, 9-(dimethylamino)-3-(4-methylphenyl)-
13-(dimethylamino)-5-(4-methylphenyl)-8-thia-3,5,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,9,11-pentaen-6-one | [Molecular Formula]
C18H16N4OS | [MOL File]
869802-73-3.mol | [Molecular Weight]
336.41 |
| Hazard Information | Back Directory | [Uses]
A-850002 is a metabotropic glutamate receptor (mGluR) antagonist (IC50=27 nM) that significantly attenuates spontaneous pain behavior after skin incision in rats. A-850002 can be used for analgesia research[1]. | [IC 50]
rat mGluR1: 41 nM (Ki) | [References]
[1] Chang Z Zhu, et al. Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats. European journal of pharmacology 580.3 (2008): 314-321. DOI:10.1016/j.ejphar.2007.09.047 |
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