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FP0429 is a full mGlu4 agonist and partial mGlu8 agonist with EC50 values of 48.3 μM and 56.2 μM, respectively[1]. | [References]
[1] Schann S, et al. Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4856-60. DOI:10.1016/j.bmcl.2006.06.062 |
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