| Identification | Back Directory | [Name]
DG2 | [CAS]
871340-88-4 | [Synonyms]
S6K1INDG2
S6K1-IN-DG2
S6K1 IN DG2
S6K1InhibitorDG2
S6K1-Inhibitor-DG2
S6K1 Inhibitor DG2
DG2 - S6K1 Inhibitor DG2
3-bromo-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2H-pyrazolo[3,4-d]pyrimidine | [Molecular Formula]
C16H17BrN6O | [MDL Number]
MFCD22580420 | [MOL File]
871340-88-4.mol | [Molecular Weight]
389.25 |
| Chemical Properties | Back Directory | [Boiling point ]
601.0±55.0 °C(Predicted) | [density ]
1.561±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 100mg/mL, clear, pale yellow | [form ]
Solid | [pka]
9.29±0.50(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
S6K1-IN-DG2 is a potent and selective inhibitor of p70 ribosomal S6 kinase 1 (S6K1). S6K1-IN-DG2 is also ATP-competitive and cell-permeable. | [Uses]
S6K1-IN-DG2 (Compound 66) is a p70S6K inhibitor (IC50: < 100 nM)[1]. | [References]
[1] Neel K. Anand, et al. Kinase modulators and methods of use. Patent. WO2005117909. |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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