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87238-52-6

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87238-52-6 Structure

87238-52-6 Structure
IdentificationBack Directory
[Name]

Ritipenemacoxil
[CAS]

87238-52-6
[Synonyms]

FCE 22891
[14C]-FCE22891
4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-, (acetyloxy)methyl ester, (5R,6S)-
[Molecular Formula]

C13H16N2O8S
[MOL File]

87238-52-6.mol
[Molecular Weight]

360.34
Chemical PropertiesBack Directory
[Boiling point ]

656.0±55.0 °C(Predicted)
[density ]

1.57±0.1 g/cm3(Predicted)
[pka]

13.31±0.50(Predicted)
Hazard InformationBack Directory
[Uses]

Ritipenem acoxil (FCE 22891; RIPM-AC) is an oral active beta-lactamase antibiotic and can be used for study of bacterial pneumonia[1].
[References]

[1] Saito A, et al. [A comparative study on the efficacies of ritipenem acoxil and cefotiam hexetil in bacterial pneumonia by the double-blind method]. Jpn J Antibiot. 1996 Feb;49(2):144-74. Japanese. PMID:8721077
Safety DataBack Directory
[Toxicity]

LD50 in male, female mice, male, female rats (mg/kg): 4363, 6167, >5000, >5000 orally (Brughera)
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