ChemicalBook--->CAS DataBase List--->872993-05-0

872993-05-0

872993-05-0 Structure

872993-05-0 Structure
IdentificationBack Directory
[Name]

(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
[CAS]

872993-05-0
[Synonyms]

RVD1
Resolvin D1
resolvin D1, CID73755062
Resolvin D1 Exclusive
OIWTWACQMDFHJG-CCFUIAGSSA-N
Resolvin D1 MaxSpec? Standard
(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-
[Molecular Formula]

C22H32O5
[MDL Number]

MFCD11045851
[MOL File]

872993-05-0.mol
[Molecular Weight]

376.49
Chemical PropertiesBack Directory
[storage temp. ]

Store at -80°C,protect from light
[solubility ]

DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml
[form ]

Liquid
[color ]

Colorless to light yellow
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319
[Precautionary statements ]

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
Hazard InformationBack Directory
[Uses]

Resolvin D1 is used to protect against hepatic injury and heart failure, specifically in rats. Also used as a means to attenuate the inflammatory reaction.
[in vivo]

Resolvin D1 (RvD1) (100-1000 ng; i.p.; daily on days 10) improves RA (rheumatoid arthritis) clinical endpoints in arthritic mice[3].

Animal Model:18-20?g thirty 8-week-old female DBA/1J mice (collagen antibody-induced arthritis (CAIA))[3]
Dosage:100, 500, and 1000?ng (or 1000 ng, daily on days 4-10)
Administration:i.p. injection; daily on days 10
Result:Exhibit a reduced arthritic score.
[IC 50]

Human Endogenous Metabolite
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