| Identification | Back Directory | [Name]
1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine | [CAS]
874590-32-6 | [Synonyms]
M1001
1,1-dioxo-N-(2-pyrrolidin-1-ylphenyl)-1,2-benzothiazol-3-amine | [Molecular Formula]
C17H17N3O2S | [MDL Number]
MFCD06761257 | [MOL File]
874590-32-6.mol | [Molecular Weight]
327.4 |
| Chemical Properties | Back Directory | [Boiling point ]
526.1±52.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 250 mg/mL (763.59 mM; Need ultrasonic) | [form ]
A solid | [pka]
5.38±0.40(Predicted) | [color ]
Light green to green |
| Hazard Information | Back Directory | [Uses]
M1001 is a weak hypoxia-inducible factor-2α (HIF-2α) agonist. M1001 can bind to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 can be used in chronic kidney disease research[1]. | [storage]
Store at -20°C | [References]
[1] Wu D, et al. Bidirectional modulation of HIF-2 activity through chemical ligands. Nat Chem Biol. 2019 Feb 25. DOI:10.1038/s41589-019-0234-5 |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 13348960310; |
| Website: |
https://www.weikeqi-biotech.com/ |
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