| Identification | Back Directory | [Name]
FLOMETOQUIN | [CAS]
875775-74-9 | [Synonyms]
FLOMETOQUIN
2-Ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinolin-4-yl?methyl?carbonate
Carbonic acid, 2-ethyl-3,7-dimethyl-6-[4-(trifluoromethoxy)phenoxy]-4-quinolinyl methyl ester | [Molecular Formula]
C22H20F3NO5 | [MOL File]
875775-74-9.mol | [Molecular Weight]
435.39 |
| Chemical Properties | Back Directory | [Melting point ]
115 - 118°C | [Boiling point ]
490.0±45.0 °C(Predicted) | [density ]
1.291±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
5.16±0.50(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C22H20F3NO5/c1-5-17-13(3)20(30-21(27)28-4)16-11-19(12(2)10-18(16)26-17)29-14-6-8-15(9-7-14)31-22(23,24)25/h6-11H,5H2,1-4H3 | [InChIKey]
FMPFURNXXAKYNE-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)OC1C2C(N=C(CC)C=1C)=CC(C)=C(OC1=CC=C(OC(F)(F)F)C=C1)C=2 |
| Hazard Information | Back Directory | [Uses]
Flometoquin is a pesticide. It is also used in other insecticidal compositions containing flometoquin and anabasine as active ingredients. An agrochemical compound. | [Production Methods]
Commercial production of flometoquin follows a multi step quinoline assembly route described which includes regioselective chlorination, esterification, and nitration to build a highly substituted aromatic intermediate. This intermediate is then coupled with 4 (trifluoromethoxy)phenol via an SNAr reaction to introduce the key phenoxy group. After catalytic reduction of the nitro group, the resulting anthranilic ester undergoes cyclisation with diethyl ketone to form the quinolinone core, which is subsequently converted into the final methyl carbonate insecticide structure. Industrial production scales this sequence using controlled chlorination, catalytic hydrogenation, and solvent managed cyclisation steps to deliver technical grade flometoquin. | [Mechanism of action]
Mitochondrial complex III electron transport inhibitors – Qi site | [Pesticide Type]
Insecticide; Acaricide |
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| Company Name: |
Madision Biomedical Co., Ltd.
|
| Tel: |
028-87439248 19150327610;15114076748 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList30539/0_EN.htm |
| Company Name: |
Cool Pharm, Ltd
|
| Tel: |
021-58581007 18019463053 |
| Website: |
http://www.coolpharm.com.cn |
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