| Identification | Back Directory | [Name]
LM 985 | [CAS]
87626-56-0 | [Synonyms]
LM 985
NSC-293015
87626-57-1 (Hydrochloride)
Flavone acetic acid diethanolamine ester
Oxo-4-phenyl-2,4,H-1-benzopyran-8-yl 2-diethylaminoethyl acetate HCl
4-Oxo-2-phenyl-4H-1-benzopyran-8-acetic acid 2-(diethylamino)ethyl ester
4H-1-Benzopyran-8-acetic acid, 4-oxo-2-phenyl-, 2-(diethylamino)ethyl ester | [Molecular Formula]
C23H25NO4 | [MDL Number]
MFCD31544455 | [MOL File]
87626-56-0.mol | [Molecular Weight]
379.45 |
| Chemical Properties | Back Directory | [Boiling point ]
533.0±50.0 °C(Predicted) | [density ]
1.178±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
9.22±0.25(Predicted) |
| Hazard Information | Back Directory | [Uses]
LM985 is one of a series of compounds based on the flavone ring structure, with anti-tumor activities. | [in vivo]
LM985 (200 mg/kg, s.c.) shows moderate activity against MAC 13, and after repeated injection 7 days, responses are considerably enhanced[2]. | [storage]
Store at -20°C | [References]
[1] M. C. Bibby, et al. Factors involved in the anti-cancer activity of the investigational agents LM985 (flavone acetic acid ester) and LM975 (flavone acetic acid). Br J Cancer. 1987 Feb; 55(2): 159-163.
[2] J. A. Double, et al. Pharmacokinetics and anti-tumour activity of LM985 in mice bearing transplantable adenocarcinomas of the colon. Br J Cancer. 1986 Oct; 54(4): 595-600. |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|