| Identification | Back Directory | [Name]
2-(3,4-Dichlorophenyl)-4-fluoroaniline | [CAS]
877179-04-9 | [Synonyms]
2-amino-5-fluoro-3,4-dichlorobenzene
2-(3,4-Dichlorophenyl)-4-fluoroaniline
3',4'-Dichloro-5-fluorobiphenyl-2-amine
3',4'-Dichloro-5-fluorobiphenyl-2-amine
3',4'-dichloro-5-fluoro-[1,1'-biphenyl]-2-aMine
[1,1']-biphenyl-2-aMine-3',4'-dichloro-5-fluoro | [EINECS(EC#)]
700-287-9 | [Molecular Formula]
C12H8Cl2FN | [MDL Number]
MFCD19440920 | [MOL File]
877179-04-9.mol | [Molecular Weight]
256.1 |
| Chemical Properties | Back Directory | [Boiling point ]
357℃ at 101.3kPa | [density ]
1.47 at 20℃ | [storage temp. ]
Sealed in dry,2-8°C | [pka]
3.22±0.10(Predicted) | [Appearance]
White to off-white Solid | [LogP]
4.3 at 22℃ and pH7 |
| Hazard Information | Back Directory | [Synthesis]
8.15 g (97%, 0.042 mol) of 3,4-dichlorophenylboronic acid are initially charged in 50 g of water and 50 g toluene. Subsequently, 18.7 g (0.085 mol) of potassium phosphate and 8.2 g (98%, 0.042 mol) of 2-bromo-4-fluoroaniline are added. After blanketing with nitrogen, 0.014 g (0.00002 mol) of 1,1'-bis(di-test-butyl phosphine) ferrocene palladium dichloride is added, and the mixture is stirred for two hours at 79-81° C. The organic phase is separated and evaporated under reduced pressure, leaving 10.5 g of an oil-crystallized 2-(3,4-Dichlorophenyl)-4-fluoroaniline.
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DoEasy Pharma Co., Ltd.
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Nextpeptide Inc
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