| Identification | Back Directory | [Name]
PD 113270 | [CAS]
87860-37-5 | [Synonyms]
PD 113270
CL-1565-B
Antibiotic CL-1565B
6-[3,6-Dihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetrenyl]-5,6-dihydro-2H-pyran-2-one | [Molecular Formula]
C19H27O8P | [MOL File]
87860-37-5.mol | [Molecular Weight]
414.387 |
| Chemical Properties | Back Directory | [Boiling point ]
687.744±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.350±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
1.843±0.10(predicted) |
| Hazard Information | Back Directory | [Description]
The novel fermentation products fostriecin and analogs PD 113,270 and PD 113,271 are structurally related polyene lactone phosphates that have antitumor activity in vitro and in vivo. | [Uses]
PD 113270 (CL 1565-B) is an antitumor agent. PD 113270 exhibits inhibitory effects to yeasts[1]. | [References]
[1] Tunac J B, et, al. Novel antitumor agents CI-920, PD 113,270 and PD 113,271. I. Taxonomy, fermentation and biological properties. J Antibiot (Tokyo). 1983 Dec;36(12):1595-600. DOI:10.7164/antibiotics.36.1595
[2] Mamber SW, et, al. Antimycotic effects of the novel antitumor agents fostriecin (CI-920), PD 113,270 and PD 113,271. J Antibiot (Tokyo). 1986 Oct;39(10):1467-72. DOI:10.7164/antibiotics.39.1467 |
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