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87896-52-4

87896-52-4 Structure

87896-52-4 Structure
IdentificationBack Directory
[Name]

A 58365A
[CAS]

87896-52-4
[Synonyms]

A 58365A
(-)-3-Carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-6-indolizinepropanoic acid
(S)-3-carboxy-1,2,3,5-tetrahydro-8-hydroxy-5-oxo-6-indolizinepropanoic acid
6-(2-carboxyethyl)-8-hydroxy-5-oxo-2,3-dihydro-1H-indolizine-3-carboxylic acid
[Molecular Formula]

C12H13NO6
[MOL File]

87896-52-4.mol
Hazard InformationBack Directory
[Description]

A 58365 A is an angiotensin converting enzyme (ACE) inhibitor isolated from Streptomyces chromofuscus. It is used to treat hypertension and congestive heart failure.
[Uses]

A 58365A is a potent angiotensin converting enzyme (ACE) inhibitor[1].
[References]

[1] Hunt AH, et al. Structure elucidation of A58365A and A58365B, angiotensin converting enzyme inhibitors produced by Streptomyces chromofuscus. J Antibiot (Tokyo). 1988 Jun;41(6):771-9. DOI:10.7164/antibiotics.41.771
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