| Identification | Back Directory | [Name]
N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)-N-(2-pyridinylmethyl)amine | [CAS]
879070-72-1 | [Synonyms]
2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-
N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)-N-(2-pyridinylmethyl)amine | [Molecular Formula]
C18H14N4O | [MOL File]
879070-72-1.mol | [Molecular Weight]
302.33 |
| Hazard Information | Back Directory | [Uses]
DC07090 is a potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM[1]. | [References]
[1] Ma GH, et al. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Eur J Med Chem. 2016 Nov 29;124:981-991. DOI:10.1016/j.ejmech.2016.10.019 |
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