| Identification | Back Directory | [Name]
Pentanoic acid, 5-[(3-amino-3-carboxypropyl)thio]- | [CAS]
88096-02-0 | [Synonyms]
CBHcy
Pentanoic acid, 5-[(3-amino-3-carboxypropyl)thio]- | [Molecular Formula]
C9H17NO4S | [MDL Number]
MFCD28160456 | [MOL File]
88096-02-0.mol | [Molecular Weight]
235.3 |
| Hazard Information | Back Directory | [Description]
CBHcy is an inhibitor of human betaine-homocysteine S-methyltransferase (BHMT). | [Uses]
CBHcy is an inhibitor for betaine-homocysteine S-methyltransferase (BGMT), with an IC50 of 0.09 μM. CBHcy upregulates the plasma total homocysteine and causes transient hyperhomocysteinemia in mice model[1]. | [References]
[1] Collinsova M, et al., Inhibition of betaine-homocysteine S-methyltransferase causes hyperhomocysteinemia in mice. J Nutr. 2006 Jun;136(6):1493-7. DOI:10.1093/jn/136.6.1493 |
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