| Identification | Back Directory | [Name]
6-O-2-Propyn-1-yl-D-galactose | [CAS]
881895-59-6 | [Synonyms]
6-O-2-Propyn-1-yl-D-galactose
D-Galactose, 6-O-2-propyn-1-yl- | [Molecular Formula]
C9H14O6 | [MDL Number]
MFCD32201130 | [MOL File]
881895-59-6.mol | [Molecular Weight]
218.2 |
| Hazard Information | Back Directory | [Uses]
6-O-2-Propyn-1-yl-D-galactose is a nonclaevable glycolinker for the functionalization of cytotoxic agents and applications in antibody-agent conjugation. 6-O-2-Propyn-1-yl-D-galactose is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
Non-cleavable Linker | [References]
[1] Ekholm FS, et al. Introducing Glycolinkers for the Functionalization of Cytotoxic Drugs and Applications in Antibody-Drug Conjugation Chemistry. ChemMedChem. 2016 Nov 21;11(22):2501-2505. DOI:10.1002/cmdc.201600372 |
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