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882420-22-6

882420-22-6 Structure

882420-22-6 Structure
IdentificationBack Directory
[Name]

Erlotinib Hydrochloride iMpurity
[CAS]

882420-22-6
[Synonyms]

OSI-356
Erlotinib Chloro
Hydroxy Erlotinib
4-Hydroxy Erlotinib
Erlotinib Impurity 10
Erlotinib Impurity 14
Erlotinib Impurity 17
Erlotinib Hydrochloride IMP
Erlotinib 4-Hydroxy Metabolite
3-Ethynylailine Hydrochloride 1
4-Hydroxy Erlotinib Hydrochloride
Erlotinib Impurity 13 Hydrobromide
ethyl 2,6-diamino-3,4-bis(2-methoxyethoxy)benzoate dihydrochloride
Phenol, 4-[[6,7-bis(2-methoxyethoxy)-4-quinazolinyl]amino]-2-ethynyl-
(Z)-N-(3-(2-chlorovinyl)phenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Erlotinib impurity 6/Erlotinib Hydroxy Metabolite/4-Hydroxy Erlotinib/4-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)-2-ethynylphenol
[Molecular Formula]

C22H23N3O5
[MDL Number]

MFCD30741276
[MOL File]

882420-22-6.mol
[Molecular Weight]

409.44
Chemical PropertiesBack Directory
[CAS DataBase Reference]

882420-22-6
Hazard InformationBack Directory
[Synthesis]

A mixture of N'-[2-cyano-4,5-bis(2-methoxyethoxy)phenyl]-N,N-dimethyl-formamidine (compound of Formula II) 60g, with m-aminophenylacetylene (compound of Formula III) 30g, and acetic acid 300mL, was heated with stirring at a temperature of 95~105℃ for 20~4
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