| Identification | Back Directory | [Name]
manassantin A | [CAS]
88497-87-4 | [Synonyms]
manassantin A
Saucernetin A
Manassantin A-RM
(-)-α,α'-[(Tetrahydro-3,4-dimethyl-2,5-furandiyl)bis[(2-methoxy-4,1-phenylene)oxyethane-1,1-diyl]]bis[3,4-dimethoxybenzenemethanol]
Benzenemethanol, α,α'-[[(2S,3R,4R,5S)-tetrahydro-3,4-dimethyl-2,5-furandiyl]bis[(2-methoxy-4,1-phenylene)oxy-(1R)-ethylidene]]bis[3,4-dimethoxy-, (αR,α'R)- | [Molecular Formula]
C42H52O11 | [MDL Number]
MFCD01744932 | [MOL File]
88497-87-4.mol | [Molecular Weight]
732.862 |
| Chemical Properties | Back Directory | [Melting point ]
82-85℃ | [Boiling point ]
836.0±65.0 °C(Predicted) | [density ]
1.172±0.06 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
2-8°C | [form ]
solid | [pka]
13.05±0.20(Predicted) | [InChIKey]
UOJVSXNASPZQFU-UHFFFAOYSA-N | [SMILES]
O1C(C(C(C1c4cc(c(cc4)OCCC(O)c5cc(c(cc5)OC)OC)OC)C)C)c2cc(c(cc2)OCCC(O)c3cc(c(cc3)OC)OC)OC |
| Safety Data | Back Directory | [WGK Germany ]
WGK 3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
Manassantin A is a potent inhibitor of hypoxia-inducible factor 1 (HIF-1) activity. Also, it is an herbal medicine isolated from Saururus chinensis which inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in bone marrow-derived mast cells (BMMCs) | [Definition]
ChEBI: A lignan isolated from Saururus cernuus and Saururus chinensis and has been shown to exhibit antineoplastic activity. | [General Description]
This substance is supplied with certified chromatographic purity. The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Carl Roth offre
|
| Tel: |
03.88.94.82.42 |
| Website: |
www.carlroth.com |
|