| Identification | Back Directory | [Name]
H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE | [CAS]
88546-74-1 | [Synonyms]
DPRO-PHE-ARG-CMK
DPRO-PHE-ARG-CHLOROMETHYLKETONE
H-D-PRO-PHE-ARG-CHLOROMETHYLKETONE
H-D-Pro-Phe-Arg-chloromethylketone trifluoroacetate salt | [Molecular Formula]
C21H31ClN6O3 | [MDL Number]
MFCD00237853 | [MOL File]
88546-74-1.mol | [Molecular Weight]
450.96 |
| Chemical Properties | Back Directory | [density ]
1.37±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Solid | [pka]
13.01±0.46(Predicted) | [color ]
White to off-white | [Sequence]
{d-Pro}-Phe-{Arg-Chloromethylketone} |
| Hazard Information | Back Directory | [Uses]
D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation[1]. | [References]
[1] Katrin F Nickel, et al. Factor XII as a Therapeutic Target in Thromboembolic and Inflammatory Diseases. Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):13-20. DOI:10.1161/ATVBAHA.116.308595 |
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