| Identification | Back Directory | [Name]
CD 349 | [CAS]
88594-08-5 | [Synonyms]
CD 349
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[2-(nitrooxy)propyl]5-[3-(nitrooxy)propyl] ester | [MDL Number]
MFCD00870080 | [MOL File]
88594-08-5.mol |
| Hazard Information | Back Directory | [Description]
CD-349 is a calcium channel antagonist potentially for the treatment of angina pectoris and hypertension. CD-349 inhibited the noradrenaline (NA)-induced contraction of aortas in Ca2(+)-free medium. The blocking effect of CD349 on neuronal Ca2+ influx, in combination with a cerebral vasodilatory action, may contribute to a favorable effect on ischemic brain damage. | [Uses]
CD-349 is an active compound. | [References]
[1] Inhibition of adenosine 3′, 5′-cyclic monophosphate phosphodiesterase by CD-349, a novel 1, 4-dihydropyridine derivative: effect of EGTA on the inhibitory activity |
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