| Identification | Back Directory | [Name]
LEUMORPHIN (HUMAN) | [CAS]
88846-98-4 | [Synonyms]
LEUMORPHIN (HUMAN)
PREPROENKAPHALIN B (226-254) (HUMAN)
L-Alanine, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-phenylalanyl-L-lysyl-L-valyl-L-valyl-L-threonyl-L-arginyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-α-aspartyl-L-prolyl-L-asparaginyl-L-alanyl-L-tyrosyl-L-serylglycyl-L-α-glutamyl-L-leucyl-L-phenylalanyl-L-α-aspart... | [Molecular Formula]
C150H224N42O46 | [MDL Number]
MFCD00079874 | [MOL File]
88846-98-4.mol | [Molecular Weight]
3351.64 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [Sequence]
Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-Arg-Ser-Gln-Glu-Asp-Pro-Asn-Ala-Tyr-Ser-Gly-Glu-Leu-Phe-Asp-Ala |
| Hazard Information | Back Directory | [Uses]
Leumorphin, human is a potent kappa opioid receptor (κ opioid receptor) agonist. Leumorphin, human inhibits the contraction of the myenteric plexus-longitudinal muscle preparation of the guinea pig ileum[1]. | [References]
[1] M Suda, K Nakao, et al. Human leumorphin is a potent, kappa opioid receptor agonist. Neurosci Lett. 1984 Sep 7;50(1-3):49-52. DOI:10.1016/0304-3940(84)90460-9 |
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