ChemicalBook--->CAS DataBase List--->89194-77-4

89194-77-4

89194-77-4 Structure

89194-77-4 Structure
IdentificationBack Directory
[Name]

bisaramil
[CAS]

89194-77-4
[Synonyms]

yutac
bisaramil
4-Chlorobenzoic acid (1R,5S)-3-ethyl-7-methyl-3,7-diazabicyclo[3.3.1]nonan-9-yl ester
[Molecular Formula]

C17H23C1N2O2.HCl
[MDL Number]

MFCD00864734
[MOL File]

89194-77-4.mol
[Molecular Weight]

322.83
Chemical PropertiesBack Directory
[Boiling point ]

404.0±45.0 °C(Predicted)
[density ]

1.23±0.1 g/cm3(Predicted)
[pka]

8.26±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Bisaramil is an orally active antiarrhythmic agent. Bisaramil exerts concentration dependent inhibitory effect on PMA-stimulated free radical generation and prolonged the time lag concentration dependently[1][2].
[Definition]

ChEBI: Bisaramil is a benzoate ester.
[References]

[1] M K Pugsley, et al. Effects of bisaramil, a novel class I antiarrhythmic agent, on heart, skeletal muscle and brain Na+ channels. Eur J Pharmacol. 1998 Jan 19;342(1):93-104. DOI:10.1016/s0014-2999(97)01420-9
[2] M Paróczai, et al. Bisaramil and antiarrhythmics as inhibitors of free radical generation. Pharmacol Res. 1997 Apr;35(4):279-85. DOI:10.1006/phrs.1997.0128
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