| Hazard Information | Back Directory | [Uses]
GSK 269984A, is an EP1 receptor antagonist with a pi of 8.1. | [in vivo]
GSK-269984A demonstrates an ED50 of 2.6 mg/kg (po), with the 10 mg/kg dose showing equivalent reversal of hypersensitivity to the standard. GSK-269984A displays moderate blood clearance in the rat
and dog and high clearance in the monkey which is reflected in the half-life for each species[1]. | [IC 50]
EP1: 7.9 (pIC50) | [storage]
Store at -20°C |
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