| Identification | Back Directory | [Name]
1H-Indole-1,3-diacetamide, N3-(2,3-dihydro-1,4-benzodioxin-6-yl)-N1,N1-diethyl-α3-oxo- | [CAS]
893983-51-2 | [Synonyms]
1H-Indole-1,3-diacetamide, N3-(2,3-dihydro-1,4-benzodioxin-6-yl)-N1,N1-diethyl-α3-oxo- | [Molecular Formula]
C24H25N3O5 | [MOL File]
893983-51-2.mol | [Molecular Weight]
435.47 |
| Hazard Information | Back Directory | [Uses]
ZINC09518833 is a α-ketoamide nonpeptidic proteasome inhibitor with an IC50 value of 12.4 μM. ZINC09518833 binds both primed and nonprimed sites of the proteasome. ZINC09518833 is promising for research of multiple myeloma (MM)[1]. | [Definition]
ChEBI: 2-[1-[2-(diethylamino)-2-oxoethyl]-3-indolyl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoacetamide is a member of indoles. | [References]
[1] Zhou J, et al. Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation[J]. ACS Medicinal Chemistry Letters, 2024. |
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