| Identification | Back Directory | [Name]
MOSAPRAMINE | [CAS]
89419-40-9 | [Synonyms]
MOSAPRAMINE
Clospipramine
MOSAPRAMINE USP/EP/BP
5H-Dibenz[b,f]azepine, spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one deriv.
1'-[3-[(3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepin)-5-yl]propyl]hexahydrospiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one
(±)-1’-[3-(3-Chloro-10-11-dihydro-5H-dibenz[b，f]azepin-5-y1)propyl]hexahydrospim[irnidazo[1，2-α]pyridine-3(2H)，4'-piperidin]-2-one
Spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one, 1'-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]hexahydro- (9CI)
Spiro[imidazo[1,2-a]pyridine-3(2H),4'-piperidin]-2-one, 1'-[3-(3-chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]hexahydro-, (+-)- | [Molecular Formula]
C28H35ClN4O | [MDL Number]
MFCD00867739 | [MOL File]
89419-40-9.mol | [Molecular Weight]
479.06 |
| Hazard Information | Back Directory | [Chemical Properties]
Mosapramine dihydrochloride: C28H35C1N4O·2HCl. [98043-60-8]. White crystals, melting point 271°C. Acute toxicity LD50 in male and female mice (mg/kg): 1008, 1293 mg/kg for oral administration; 74, 116 mg/kg for intraperitoneal injection; 1147, 1264 mg/kg for subcutaneous injection. | [Uses]
Mosapramine is a anti-psychotic as it is used in the treatment of schizophrenia. | [Definition]
ChEBI: Mosapramine is a racemate comprising equimolar amounts of (R)- and (S)-mosapramine. It is a second-generation antipsychotic used for the treatment of schizophrenia. It has a role as a second generation antipsychotic and a dopaminergic antagonist. It contains a (S)-mosapramine and a (R)-mosapramine. |
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