ChemicalBook--->CAS DataBase List--->894309-72-9

894309-72-9

894309-72-9 Structure

894309-72-9 Structure
IdentificationBack Directory
[Name]

Thiourea, N-[(2-bromophenyl)methyl]-N'-(4-nitrophenyl)-
[CAS]

894309-72-9
[Synonyms]

InhA-IN-4
Thiourea, N-[(2-bromophenyl)methyl]-N'-(4-nitrophenyl)-
[Molecular Formula]

C14H12BrN3O2S
[MOL File]

894309-72-9.mol
[Molecular Weight]

366.23
Chemical PropertiesBack Directory
[Boiling point ]

497.2±55.0 °C(Predicted)
[density ]

1.606±0.06 g/cm3(Predicted)
[pka]

11.07±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

InhA-IN-4 (TU14) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 15.6 μM[1].
[References]

[1] Do?an ?D, et al. Design and synthesis of thiourea-based derivatives as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors. Eur J Med Chem. 2020 Aug 1;199:112402. DOI:10.1016/j.ejmech.2020.112402
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