| Identification | Back Directory | [Name]
TFCA | [CAS]
895700-18-2 | [Synonyms]
TFCA
3-(3,4-Dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]-2-propenamide
2-Propenamide, 3-(3,4-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]- | [Molecular Formula]
C18H16F3NO3 | [MOL File]
895700-18-2.mol | [Molecular Weight]
351.32 |
| Hazard Information | Back Directory | [Biological Activity]
TFCA is a Liver X receptor α (LXRα) antagonist th at reduces lipid accumulation and fatty liver in mice. Apparently TFCA binds to the LXR? ligand binding domain and induces interaction with NCoR corepressor. |
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