| Identification | Back Directory | [Name]
5,4'-DIHYDROXY-7-METHOXYISOFLAVONE-4'-O-GLUCOSIDE | [CAS]
89595-66-4 | [Synonyms]
PRUNITRIN
Prunetinoside
Prunetin 5-glucoside
PRUNETIN-4'-GLUCOSIDE
Prunetin 5-O-β-D-glucopyranoside
PRUNETIN-4'-GLUCOSIDE 89595-66-4
5,4'-DIHYDROXY-7-METHOXYISOFLAVONE-4'-O-GLUCOSIDE
4H-1-Benzopyran-4-one, 5-(β-D-glucopyranosyloxy)-3-(4-hydroxyphenyl)-7-methoxy- | [Molecular Formula]
C22H22O10 | [MDL Number]
MFCD00272143 | [MOL File]
89595-66-4.mol | [Molecular Weight]
446.4 |
| Hazard Information | Back Directory | [Uses]
Prunetin 5-O-β-D-glucopyranoside is an isoflavone isolated from extracts of Potentilla astracanica. Prunetin 5-O-β-D-glucopyranoside is a potent and uncompetitive inhibitor of α-glucosidase, with an IC50 of 56.05 μg/mL. Prunetin 5-O-β-D-glucopyranoside can be used for the research of type-2 diabetes[1]. | [References]
[1] ??hreto?lu D, et, al. α-Glucosidase inhibitory effect of Potentilla astracanica and some isoflavones: Inhibition kinetics and mechanistic insights through in vitro and in silico studies. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1062-1070. DOI:10.1016/j.ijbiomac.2017.07.132 |
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