| Identification | Back Directory | [Name]
4H-1,2,4-Benzothiadiazine-3-propanamide, 6-methyl-N-[3-(tricyclo[3.3.1.13,7]dec-1-yloxy)propyl]-, 1,1-dioxide | [CAS]
896684-04-1 | [Synonyms]
BTD-TRPC5 activator
4H-1,2,4-Benzothiadiazine-3-propanamide, 6-methyl-N-[3-(tricyclo[3.3.1.13,7]dec-1-yloxy)propyl]-, 1,1-dioxide | [Molecular Formula]
C24H33N3O4S | [MDL Number]
MFCD32206722 | [MOL File]
896684-04-1.mol | [Molecular Weight]
459.6 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [SMILES]
O=C(NCCCOC1(C2)C[C@H](C[C@H]2C3)C[C@H]3C1)CCC(NS4(=O)=O)=NC5=C4C=CC(C)=C5 |
| Hazard Information | Back Directory | [Uses]
BTD is a selective transient receptor potential canonical 5 (TRPC5) activator. BTD can be used for the research of neurological disease[1]. | [Biological Activity]
BTD is a potent and selective activator of the transient receptor potential canonical channel 5 (TRPC5). BTD can also activate heteromeric channels composed of TRPC5 and its closest relatives TRPC1 or TRPC4. | [storage]
Store at -20°C | [References]
[1] Beckmann H,et al. A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels. Cell Calcium. 2017;66:10-18. DOI:10.1016/j.ceca.2017.05.012 |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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