| Identification | Back Directory | [Name]
Benzamide, 2-[[(4-chlorophenyl)sulfonyl]amino]-N-(4-methoxy-2-nitrophenyl)- | [CAS]
898440-60-3 | [Synonyms]
SOAT-IN-1
Benzamide, 2-[[(4-chlorophenyl)sulfonyl]amino]-N-(4-methoxy-2-nitrophenyl)- | [Molecular Formula]
C20H16ClN3O6S | [MOL File]
898440-60-3.mol | [Molecular Weight]
461.88 |
| Hazard Information | Back Directory | [Uses]
SOAT-IN-1 (compound 40) is a potent and selective sodium-dependent organic anion transporter (SOAT) inhibitor with IC50 values of 1.6, 14.3 μM for SOAT, NTCP, respectively[1]. | [References]
[1] Wannowius M, et al. Structure-Activity Relationships and Target Selectivity of Phenylsulfonylamino-Benzanilide Inhibitors Based on S1647 at the SLC10 Carriers ASBT, NTCP, and SOAT. J Med Chem. 2024 Oct 17. DOI:10.1021/acs.jmedchem.4c01743 |
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