| Identification | Back Directory | [Name]
Gastrofensin AN 5 free base | [CAS]
89845-16-9 | [Synonyms]
Gastrofensin AN 5 free base
Carbamic acid, [4-(4-chlorophenyl)-1,2,3,4-tetrahydro-2-methyl-8-isoquinolinyl]-, ethyl ester (9CI) | [Molecular Formula]
C19H21ClN2O2 | [MDL Number]
MFCD02183963 | [MOL File]
89845-16-9.mol | [Molecular Weight]
344.84 |
| Hazard Information | Back Directory | [Uses]
Gastrofensin AN 5, is a 4-phenyl-tetrahydroisoquinoline derivative, that can be used as an antiulcer agent. | [in vivo]
Gastrofensin AN 5 supresses the formation of ulcers in all experimental models. From the broad pharmacological studies of Gastrofensin AN 5 on this model it can be seen that even a dose of 0.100 mg/kg has a high antiulcer activity. The increase of the dose leads to a regular increase of the antiulcer activity, the highest suppression of the ulcer index being reaches at a dose of 1 mg/kg (86.15%). The comparative studies with Ranitidine and Cimetidine on the same experimental models of gastric ulcers show that Gastrofensin AN 5 possesses an antiulcer activity many times higher than that of the above-mentioned drugs[1]. | [storage]
Store at -20°C |
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