| Identification | Back Directory | [Name]
3'-O-(t-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine | [CAS]
89947-86-4 | [Synonyms]
3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine
3'-O-(t-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)-2'-deoxyadenosine | [Molecular Formula]
C37H45N5O5Si | [MOL File]
89947-86-4.mol | [Molecular Weight]
667.869 |
| Hazard Information | Back Directory | [Uses]
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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