| Identification | Back Directory | [Name]
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine | [CAS]
899827-82-8 | [Synonyms]
ClofarabineImpurity16
2'-Deoxy-2'-fluoro-arabinoisoguanosine
2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine
2H-Purin-2-one, 6-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-
6-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-2H-purin-2-one
6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one
2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine,Clofara bine’s impurity B,DNA and RNA synthetase inhibitor | [Molecular Formula]
C10H12FN5O4 | [MDL Number]
MFCD25542486 | [MOL File]
899827-82-8.mol | [Molecular Weight]
285.23 |
| Hazard Information | Back Directory | [Uses]
2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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