| Identification | Back Directory | [Name]
CATECHOL O-METHYLTRANSFERASE | [CAS]
9012-25-3 | [Synonyms]
COMT
EC 2.1.1.6
Catechol methyltransferase
Methyltransferase, catechol
CATECHOL O-METHYLTRANSFERASE
Catechol O-methyltransferases
CATHECHOL-O-METHYL TRANSFERASE
Catecholamine O-methyltransferase
Pyrocatechol-O-methyl Transferase
CATECHOL O-METHYLTRANSFERASE USP/EP/BP
CATECHOL-O-METHYL TRANSFERASE, <10 U/ML*
CATECHOL O-METHYLTRANSFERASE FROM &
catechol-o-methyl transferase from hog liver
Native Porcine Catechol-O-methyl Transferase
catechol O-methyltransferase from*porcine liver
S-ADENOSYL-L-METHIONINE:CATECHOL O-METHYLTRANSFERASE
COMT, Pyrocatechol-O-methyl Transferase, S-Adenosyl-L-methionine:catechol O-methyltransferase | [EINECS(EC#)]
232-727-6 | [MDL Number]
MFCD00081488 |
| Hazard Information | Back Directory | [Uses]
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain[1]. | [References]
[1] Du X, et, al. A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14. DOI:10.1073/pnas.0807219105 |
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