| Identification | Back Directory | [Name]
DI-4-ANEPPS | [CAS]
90134-00-2 | [Synonyms]
Jpw 211
DI-4-ANEPPS
NEURODYE DI-4-ANEPPS
Di-4-ANEPPS *CAS#: 90134-00-2*
6-[2-(n,n-dibutylamino)naphthyl]ethenyl-
40-pyridinium Propanesulfonate
1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridiniumb
1-(3-
sulfonatopropyl)4-[b-[2-(di-n-butylamino)-6-naphthyl]
vinyl]pyridinium Betaine
1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine
4-(2-(6-(DIBUTYLAMINO)-2-NAPHTHALENYL)ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM HYDROXIDE INNER SALT | [Molecular Formula]
C28H36N2O3S | [MDL Number]
MFCD03453609 | [MOL File]
90134-00-2.mol | [Molecular Weight]
480.66 |
| Chemical Properties | Back Directory | [Melting point ]
122–124℃ | [storage temp. ]
2-8°C | [solubility ]
DMF: soluble | [form ]
powder | [color ]
orange to red | [Appearance]
Orange solid | [ex/em]
483/686 nm (artificial membrane) | [ε(extinction coefficient)]
≥38000 at 493-499nm in methanol | [λmax]
495 nm | [Biological Applications]
Measuring membrane potential; preventing arrhythmias; probes for Na,K-ATPase reaction mechanism; assays for identifying tastespecific genes; quantum dots | [Major Application]
diagnostic assay manufacturing
hematology
histology | [InChI]
1S/C28H36N2O3S/c1-3-5-17-30(18-6-4-2)28-13-12-26-22-25(10-11-27(26)23-28)9-8-24-14-19-29(20-15-24)16-7-21-34(31,32)33/h8-15,19-20,22-23H,3-7,16-18,21H2,1-2H3 | [InChIKey]
HAPJROQJVSPKCJ-UHFFFAOYSA-N | [SMILES]
CCCCN(CCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1 |
| Hazard Information | Back Directory | [Description]
Di-4-ANEPPS is a potentiometric fluorescent dye that can be used to measure membrane potential. It displays absorption/emission maxima of 495/705 nm, respectively. The relative fluorescence changes proportionally to membrane potential at a rate of approximately 10% per 100 mV. Di-4-ANEPPS has been used to measure membrane potential in a variety of tissue and cell types as well as artificial membranes. | [Chemical Properties]
Appearance: Orange-red solid
ex/em: 483/686 nm (artificial membrane)
Extinction coefficient (ε): 39,000 L??mol??1??cm??1 (methanol) | [Uses]
Di-4-ANEPPS is a membrane potential dye which responds to changes in membrane potential monitored by fluorescence excitation changes. It is correlated to changes in the membrane potential of a cell. Dyes and metabolites. | [storage]
Store at -20°C | [References]
[1] L M LOEW. A naphthyl analog of the aminostyryl pyridinium class of potentiometric membrane dyes shows consistent sensitivity in a variety of tissue, cell, and model membrane preparations.[J]. Journal of Membrane Biology, 1992, 130 1: 1-10. DOI: 10.1007/bf00233734 | [Abs/Em Maxima]
493/708 nm |
|
| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
| Company Name: |
AnaSpec Inc
|
| Tel: |
180-04525530 18004525530 |
| Website: |
www.anaspec.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|