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902154-32-9

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902154-32-9 Structure

902154-32-9 Structure

Identification	Back Directory
[Name] N-[[[3-(1H-Imidazol-5-yl)propyl]amino]iminomethyl]cyclohexanepropanamide
[CAS] 902154-32-9
[Synonyms] UR-AK49
[Molecular Formula] C16H27N5O
[MOL File] 902154-32-9.mol
[Molecular Weight] 305.42

Chemical Properties	Back Directory
[density ] 1.24±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
[pka] 13.91±0.46(Predicted)

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[Uses] UR-AK49 (compound 11) is a human histamine H1 and H2 receptor agonist. UR-AK49 has an EC50 of 23 nM in a GTPase assay with hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 can be used in neuro-related research[1].
[IC 50] Human H₁ Receptor; H₂ Receptor
[References] [1] Xie SX, et al. N1-(3-cyclohexylbutanoyl)-N2-[3-(1H-imidazol-4-yl)propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors. J Pharmacol Exp Ther. 2006 Jun;317(3):1262-8. DOI:10.1124/jpet.106.102897

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