| Identification | Back Directory | [Name]
ML-262 | [CAS]
902502-82-3 | [Synonyms]
ML-262
ML262,ML 262
2-Thiophenecarboxamide, N-[2-(3,4-diethoxyphenyl)ethyl]-5-(4-morpholinyl)-4-phenyl- | [Molecular Formula]
C27H32N2O4S | [MOL File]
902502-82-3.mol | [Molecular Weight]
480.62 |
| Chemical Properties | Back Directory | [Boiling point ]
636.6±55.0 °C(Predicted) | [density ]
1.183±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 12.5 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml | [form ]
A crystalline solid | [pka]
14.06±0.46(Predicted) |
| Hazard Information | Back Directory | [Uses]
ML-262 is an inhibitor of hepatic lipid droplet formation (IC50=6.4 nM in murine AML-12 cells), which is associated with non-alcoholic fatty liver disease.1 ML-262 does not induce cytotoxicity (up to 33 μM) or inhibit fatty acid uptake (up to 50 μM). | [storage]
Store at -20°C | [References]
[1] Zou, et al. Potent inhibitors of lipid droplet formation. 1-17 (2011). |
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