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902630-14-2

902630-14-2 Structure

902630-14-2 Structure
IdentificationBack Directory
[Name]

MMV019313
[CAS]

902630-14-2
[Synonyms]

MMV019313
[Molecular Formula]

C22H27N3O2S
[MOL File]

902630-14-2.mol
[Molecular Weight]

397.53
Chemical PropertiesBack Directory
[Boiling point ]

635.0±55.0 °C(Predicted)
[density ]

1.212±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

14.22±0.20(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

MMV019313 is a highly specific inhibitor of the bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase (FPPS/GGPPS).
[Uses]

MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 μM. MMV019313 has activity against P. falciparum (Parasite)[1].
[References]

[1] Kabeche S, et al. Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS. Bioorg Med Chem Lett. 2021 Jun 1;41:127978. DOI:10.1016/j.bmcl.2021.127978
902630-14-2 suppliers list
Company Name: DC Chemicals  
Telephone: 021-58447131 13564518121
Website: https://www.chemicalbook.com/ShowSupplierProductsList927327/0_EN.htm
Company Name: Zhejiang Huida Biotech Co., Ltd.  
Telephone: 0571-89903022 18679456698
Website: www.huidacollection.cn
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