| Identification | Back Directory | [Name]
Neochamaejasmin A | [CAS]
90411-13-5 | [Synonyms]
Neochamaejasmin
Neochamaejasmin A
Neochamaejasmine A
(2R,2'R,3R,3'R)-rel-(+)-2,2',3,3'-Tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione
[3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2R,2'R,3R,3'R)-rel-(+)- | [Molecular Formula]
C30H22O10 | [MDL Number]
MFCD21333427 | [MOL File]
90411-13-5.mol | [Molecular Weight]
542.49 |
| Hazard Information | Back Directory | [Uses]
Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2]. | [References]
[1] Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71(5):842-6. DOI:10.1021/np8001223
[2] Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150. DOI:10.1155/2020/3237150 |
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Energy Chemical
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