| Identification | Back Directory | [Name]
EC 3.3.2.3 | [CAS]
9048-63-9 | [Synonyms]
EC 3.3.2.3 EPOXIDE HYDROLASE Hydratase, epoxide soluble epoxide hydrolase EPOXIDE HYDROLASE MICROSOMES, HUMAN EPOXIDE HYDROLASE, ASPERGILLUS NIGER Epoxide Hydrolase Rhodococcus rhodochrous EPOXIDE HYDROLASE, AGROBACTERIUM RADIOBACTER epoxide hydrolase from rhodococcus rhodochrous Native Rhodococcus rhodochrous Epoxide Hydrolase EPOXIDE-HYDROLASE FROM RHODOCOCCUSRHODOC HROUS, ~1 U/G EPOXIDE HYDROLASE, ASPERGILLUS NIGER, REC., FROM E. COLI* Epoxide Hydrolase, Aspergillus niger sp., recombinant E. coli Epoxide Hydrolase, Agrobacterium radiobacter, recombinant from E. coli epoxide hydrolase, aspergillus niger sp., recombinant from aspergillus niger Epoxide Hydrolase from Rhodococcus rhodochrous lyophilized powder, beige, >=0.5 U/g | [MDL Number]
MFCD01866317 |
| Hazard Information | Back Directory | [Uses]
Epoxide hydrolase is an enzyme responsible for catalyzing the reaction between epoxides and water, converting epoxide groups into diols. Epoxide hydrolase plays a key role in the metabolism of environmental pollutants and lipids, contributing to detoxification, inflammation responses, and the regulation of cardiovascular system health. Additionally, epoxide hydrolase can be used in asymmetric catalytic reactions, such as the asymmetric ring-opening of epoxides, to produce chiral drug molecules[1][2]. | [Biochem/physiol Actions]
Epoxide hydrolase is an enantioselective catalyst for the hydrolytic kinetic resolution of epoxides. | [References]
[1] Jacobsen EN. Asymmetric catalysis of epoxide ring-opening reactions. Acc Chem Res. 2000 Jun;33(6):421-31. DOI:10.1021/ar960061v |
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