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905449-84-5

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905449-84-5 Structure

905449-84-5 Structure
IdentificationBack Directory
[Name]

DBA-DM4
[CAS]

905449-84-5
[Synonyms]

DBA-DM4
Maytansine, N2'-[4-[(3-carboxypropyl)dithio]-4-methyl-1-oxopentyl]-N2'-deacetyl-
[Molecular Formula]

C42H60ClN3O12S2
[MDL Number]

MFCD32263225
[MOL File]

905449-84-5.mol
[Molecular Weight]

898.52
Chemical PropertiesBack Directory
[Boiling point ]

1041.4±65.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[pka]

4.62±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

DBA-DM4 is a agent-linker conjugate composed of a potent a tubulin inhibitor DM1 and a linker SPDP to make antibody agent conjugate (ADC)[1].
[IC 50]

Maytansinoids
[References]

[1] Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs
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Website: https://www.targetmol.cn/
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