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90596-75-1

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90596-75-1 Structure

90596-75-1 Structure
IdentificationBack Directory
[Name]

YT 146
[CAS]

90596-75-1
[Synonyms]

YT 146
YT146|||YT-146
2-(1-Octynyl)adenosine
[MDL Number]

MFCD00905325
[MOL File]

90596-75-1.mol
Hazard InformationBack Directory
[Uses]

YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist. YT 146 causes a concentreation dependent cAMP accumulation, with the EC50 of 1.5 nM. YT 146 has cardioprotective effects[1].
[IC 50]

A2AR
[References]

[1] Jun Sasamori, et al. Cardioprotective effects of 2-octynyladenosine (YT-146) in ischemic/reperfused rat hearts. J Cardiovasc Pharmacol. 2011 Feb;57(2):166-73. DOI:10.1097/FJC.0b013e318201c264
Spectrum DetailBack Directory
[Spectrum Detail]

YT 146(90596-75-1)1HNMR
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