| Identification | Back Directory | [Name]
PARG | [CAS]
9068-16-0 | [Synonyms]
PARG
PARG human
EC 3.2.1.143
PARG (BOVINE)
FNDC5 (cleaved)
PARG IMMUNOBLOT STANDARD
POLY(ADP-RIBOSE) GLYCOHYDROLASE
Irisin, Recombinant, Human (Fibronectin Type III Domain-containing Protein 5, (cleaved) | [MDL Number]
MFCD02688310 |
| Safety Data | Back Directory | [WGK Germany ]
WGK 1 | [Storage Class]
6.1D - Non-combustible acute toxic Cat.3
toxic hazardous materials or hazardous materials causing chronic effects | [Hazard Classifications]
Repr. 1B |
| Hazard Information | Back Directory | [Uses]
PARG human has been used in the digestion of sciatic nerve sections, in co-immunoprecipitation, in in vitro glycohydrolase activity assay | [Biological Activity]
Poly(ADP-ribose) glycohydrolase(PARG) hydrolyzes poly(ADP-ribose) at glycosidic(1μμ-2μμ) linkage of ribose-ribose bond to produce free ADP-ribose. It is an endo- and exo-glycosidase. PARG plays arole in DNA repair and replication. Inhibited or depleted PARG in cells aremore prone to DNA-damaging agents. PARG also averts the accumulation of PAR inthe cytoplasm and parthanatosa caspase-independent PAR-mediated type of celldeath. |
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| Company Name: |
ZSGB-BIO
|
| Telephone: |
02-400-810-9781 400810978 |
| Website: |
www.zsbio.com |
| Company Name: |
Merck KGaA
|
| Telephone: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|