| Identification | Back Directory | [Name]
Ethanone, 1-[4-nitro-5-(phenylthio)-2-thienyl]- | [CAS]
90680-28-7 | [Synonyms]
P22074
P-22074
Ethanone, 1-[4-nitro-5-(phenylthio)-2-thienyl]- | [Molecular Formula]
C12H9NO3S2 | [MOL File]
90680-28-7.mol | [Molecular Weight]
279.33 |
| Hazard Information | Back Directory | [Description]
P22074 is a USP7 inhibitor. It is not as active of an antagonist as are its halogen-substituted related compounds. | [Uses]
USP7/USP47 inhibitor 1 (compound 2) is an inhibitor of USP47, with an EC50 of 14 μM. USP7/USP47 inhibitor 1 has an EC50 of >31.6 μM for USP7. USP7/USP47 inhibitor 1 can be used for cancer research[1]. | [References]
[1] Weinstock J, et al. Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. ACS Med Chem Lett. 2012 Sep 11;3(10):789-92. DOI:10.1021/ml200276j |
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