| Identification | Back Directory | [Name]
6-bromo-3-methyl-1,3-dihydroindol-2-one
| [CAS]
90725-50-1 | [Synonyms]
6-BROMO-3-METHYLINDOLIN-2-ONE
6-bromo-3-methyl-1,3-dihydroindol-2-one
6-bromo-3-methyl-1,3-dihydro-2h-indol-2-one
6-bromo-3-methyl-2,3-dihydro-1H-indol-2-one
2H-INDOL-2-ONE, 6-BROMO-1,3-DIHYDRO-3-METHYL- | [Molecular Formula]
C9H8BrNO | [MDL Number]
MFCD15523678 | [MOL File]
90725-50-1.mol | [Molecular Weight]
226.07 |
| Chemical Properties | Back Directory | [Boiling point ]
317.3±42.0 °C(Predicted) | [density ]
1.535±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
13.43±0.40(Predicted) | [Appearance]
Off-white to light yellow Solid |
| Hazard Information | Back Directory | [Synthesis]
To a stirred solution of 2-(4-bromo-2-nitrophenyl)propionic acid (0.800 g, 2.91 mmol) dissolved in a mixture of 50% H2SO4 (6.2 mL) and EtOH (8.5 mL), Zn powder (0.76 g, 11.6 mmol) was added. The reaction was carried out at 90 °C under nitrogen protection. Subsequently, the reaction mixture was treated according to a cyclization method similar to that described in Example 6 to afford 6-bromo-3-methyl-1,3-dihydroindol-2-one (0.61 g, 93% yield). Theoretical values of elemental analysis: C, 47.82; H, 3.57; N, 6.20. measured values: C, 47.80; H, 3.78; N, 5.83. | [References]
[1] Patent: US2003/225127, 2003, A1. Location in patent: Page 14 |
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