| Identification | Back Directory | [Name]
Cyclobutanecarboxylic acid, 3-[(8'-chloro-2',3'-dihydro-2'-oxospiro[cyclohexane-1,4'(1'H)-quinazolin]-5'-yl)oxy]-, trans- | [CAS]
908570-13-8 | [Synonyms]
PDE7-IN-3
Cyclobutanecarboxylic acid, 3-[(8'-chloro-2',3'-dihydro-2'-oxospiro[cyclohexane-1,4'(1'H)-quinazolin]-5'-yl)oxy]-, trans-
Cyclobutanecarboxylic acid, 3-[(8'-chloro-2',3'-dihydro-2'-oxospiro[cyclohexane-1,4'(1'H)-quinazolin]-5'-yl)oxy]-, trans- | [Molecular Formula]
C18H21ClN2O4 | [MOL File]
908570-13-8.mol | [Molecular Weight]
364.82 |
| Chemical Properties | Back Directory | [Boiling point ]
562.9±50.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
4.36±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Pde7-in-3 (example 2) is an inhibitor of the phosphodiesterase PDE7 with potential analgesic activity. PDE7-IN-3 can be used to study inflammatory, neuropathic, visceral and nociceptive pain[1]. | [IC 50]
PDE7 | [References]
[1] Cox Peter, et al. Use of combinations of PDE7 inhibitors and alpha-2-delta ligands for the treatment of neuropathic pain. World Intellectual Property Organization, WO2006092692 A1. 2006-09-08. |
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