ChemicalBook--->CAS DataBase List--->90897-92-0

90897-92-0

90897-92-0 Structure

90897-92-0 Structure
IdentificationBack Directory
[Name]

3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
[CAS]

90897-92-0
[Synonyms]

3,4-Diflurphenylmagnesium bromide
Bromo(3,4-difluorophenyl)-magnesium
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE
Magnesium,bromo(3,4-difluorophenyl)-
magnesium,1,2-difluorobenzene-5-ide,bromide
3,4-difluorophenylmagnesium bromide solution
3,4-Difluorophenylmagnesium bromide, 0.5 M in THF
3,4-Difluorophenylmagnesium bromide, 0.50 M in THF
3,4-DifluorophenylMagnesiuM broMide, 0.50 M in 2-MeTHF
3,4-Difluorophenylmagnesium bromide solution 0.5 in THF
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE 0.5M Tetrahydrofuran
3,4-Difluorophenylmagnesium bromide,0.5M solution in THF
3,4-Difluorophenylmagnesium bromide solution 0.5 M in THF
3,4-Difluorophenyl Magnesium bromide 0.5 M in THF Cap: 100 ml
3,4-Difluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal
3,4-Difluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal§3
3,4-DIFLUOROPHENYLMAGNESIUM BROMIDE, 0.5M SOLUTION IN TETRAHYDROFURAN
3,4-DifluorophenylMagnesiuM broMide, 0.50 M solution in 2-Methyltetrahydrofuran, SpcSeal
[Molecular Formula]

C6H3BrF2Mg
[MDL Number]

MFCD00672004
[MOL File]

90897-92-0.mol
[Molecular Weight]

217.29
Chemical PropertiesBack Directory
[Boiling point ]

65 °C
[density ]

0.965 g/mL at 25 °C
[Fp ]

1 °F
[storage temp. ]

2-8°C
[form ]

Solution
[color ]

Yellow to dark brown
[Water Solubility ]

Reacts with water.
[Sensitive ]

Air & Moisture Sensitive
[InChI]

1S/C6H3F2.BrH.Mg/c7-5-3-1-2-4-6(5)8;;/h1,3-4H;1H;/q;;+1/p-1
[InChIKey]

WZHAVYGMKGPNFN-UHFFFAOYSA-M
[SMILES]

Fc1ccc([Mg]Br)cc1F
Safety DataBack Directory
[Hazard Codes ]

F,C,Xn
[Risk Statements ]

11-14-19-22-34-40-36/37
[Safety Statements ]

16-26-33-36/37/39-45-36/37
[RIDADR ]

UN 2924 3/PG 2
[WGK Germany ]

1
[Hazard Note ]

Flammable
[HazardClass ]

3
[HS Code ]

29319090
[Storage Class]

3 - Flammable liquids
[Hazard Classifications]

Acute Tox. 4 Oral
Carc. 2
Eye Irrit. 2
Flam. Liq. 2
STOT SE 3
Hazard InformationBack Directory
[Chemical Properties]

Tan liquid
[Uses]

3,4-Difluorophenylmagnesium bromide can be used:
  • To prepare 3,4-difluorophenylboronic acid, a key building block employed in the synthesis of norepinephrine transporter selective molecules.
  • In the synthesis of trimethoxybenzophenone derived tubulin polymerization inhibitors.
  • In one of the key synthetic steps for the preparation of diarylketoxime derivatives as potent MCH-1R antagonists.
  • In the synthesis of biologically important hydroxybupropion analogs useful in smoking cessation.

[Uses]

3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
[reaction suitability]

reaction type: Grignard Reaction
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