| Identification | Back Directory | [Name]
Methyl 2-oxindole-4-carboxylate | [CAS]
90924-46-2 | [Synonyms]
Nintedanib Impurity 129
4-Methoxycarbonyl-2-oxindole
Methyl 2-oxindole-4-carbo...
METHYL OXINDOLE-4-CARBOXYLATE
METHYL 2-OXINDOLE-4-CARBOXYLATE
Methyl-2-Dxoindline-4-carboxylate
Methyl 2-oxoindoline-4-carboxylate
methyl 2-oxo-2,3-dihydro-1H-indole-4-carboxylate
Methyl 2-oxindole-4-carboxylate in stock Factory
4-Indolinecarboxylicacid, 2-oxo-, methyl ester (7CI)
2-oxo-1,3-dihydroindole-4-carboxylic acid methyl ester
1H-Indole-4-carboxylic acid, 2,3-dihydro-2-oxo-, Methyl ester | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C10H9NO3 | [MDL Number]
MFCD08277245 | [MOL File]
90924-46-2.mol | [Molecular Weight]
191.18 |
| Hazard Information | Back Directory | [Synthesis]
General method: Compound 22 (15.8 mmol) or Compound 23 (15.8 mmol) was dissolved in methanol, 10 μl of 10% Pd-C catalyst was added and hydrogen was passed through. The reaction mixture was stirred for 5 hours. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated. The residue obtained was purified by recrystallization from methanol to give methyl 4-carboxylate dihydroindol-2-one. | [References]
[1] Bioorganic and Medicinal Chemistry Letters, 2015, vol. 25, # 20, p. 4557 - 4561 |
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